Any time I do lunges and squats and heavy leg days Im a zombie for two days. Rogan has been criticized for making public remarks about the vaccine which many deem irresponsible and potentially even dangerous, given his enormous platform. I went in and had a sleep study done and it was bad. Then I became a mom. https://e9595d1-i1s97x5z39rftewq2v.hop.clickbank.netIf you enjoyed the video, consider supporting the channel by making any contribution on cashapp @ https://cash.app/$JreDaily I greatly appreciate any support and hope you have a great day!For a more in depth video from Dr. Rhonda on this topic: https://www.youtube.com/watch?v=zz4YVJ4aRfgDr. In this this episode of The Matt Walker Podcast, Matt Walker & Craig Canapari continue their two part discussion behind the science of FREE when you join over 50,000 subscribers to the Podcast Notes newsletter. Dr. Rhonda Patrick (@foundmyfitness) has a Ph.D. in biomedical science and is an expert on nutritional health. This is an unofficial transcript meant for reference. COVID vaccine misinformation has been rampant you will eventually be exposed to virus at some point, so the decision/risk to consider is: do you want to be vaccinated or unvaccinated at the time of exposure? Itll tell you: hey, you should get to bed since youve been getting up at 6 oclock in the morning so you should go to bed by 10 tonight. #1474 - Dr. Rhonda Patrick Aired on May 14, 2020 * no books mentioned Joe Rogan Experience Podcast Episode #1474 Dr. Rhonda Patrick ( @foundmyfitness) has a PhD in biomedical science and is an expert on nutritional health, the brain and aging. Preview of Spotify. ZDQzNjZiNTkxODE1NzMxZjdmZjI5YTEwOTEyZjlkZjhlNWMzMWZkNjhhMGVk Amyloid beta plaques are one of the key markers of your likelihood of developing Alzheimer's. Sleep: Also helps your body cleanse out amyloid beta plaques. MWE0M2IyODlhMmZmNTBkMTkzOGQ5YmFlYzVjZGJhMDNjNGM2ZjdiNjBiODkw All notes are independently created and do not imply any sponsorship or endorsement by the source podcast. Much of the scientific studies detailing the benefits involve the dry sauna, The real benefits come when you get to 180 degrees, Frequent sauna use increases mitochondrial biogenesis and allows for improvements in mitochondrial function, Using the sauna before a workout has been shown to reduce DOMS (delayed onset muscle soreness) they dont specify for how long to use the sauna pre workout, Hyperthermia (and exercise) activates IL-6(its an inflammatory cytokine) like crazy, The greater the production of IL-6, the greater the reduction in depressive symptoms, This is the same thing released from muscle tissue after exercise, In response to this, the body has an anti-inflammatory effect, Giving people NSAIDS (nonsteroidal anti-inflammatory agents) prior to a workout, blunts IL-6 production, and many of the benefits of exercise are negated (like improved insulin sensitivity), There are studies that show hot yoga improves depressive symptoms, Its is responsible for what one might call, a dizziness feeling, at the tail end of a sauna session that feeling of oh god, I have to get out, Dynorphin binds to kapa opioid receptors in the brain, This causes a feedback response in other opioid receptors in the brain (mu opioid receptors) which bind to beta endorphins, Joe has one in his studio, he tries to do it 2-3 times a week, Hell often do it in the morning, sometimes for 2 hours, Joe gets his blood checked every 6 months, 300 grams of brussel sprouts a day increased blood glutathione plasma levels by 1.4 fold. Some we cant control like where you are born, genetics, etc. Let me know if I'm missing any. It happens when Im shifting from one sleep stage to the next. memory issues, Alzheimers-like effects) is troubling, If your brain unable to compensate, then you begin to lose motor control, Lactate needs oxygen to be able to be used, and so when you pass out lactate cant be used and causes damage, This is more an issue for larger scale head trauma like in a car crash, A little of reactive oxygen species can damage DNA that you can usually repair this, but if not it can lead to cancer, But a huge burst of it leads to a defensive mechanism to preemptively kill cells before they mutate and cause cancer (similar to what you do with radiation treatments for cancer), Inflammation in the brain leads to accumulation of, Amyloid beta plagues are one of the major pathologies associated with Alzheimers, It Generally builds up bit by bit as we age over time, but TBI can trigger them much more quickly, Plaque levels are formed immediately in TBI akin to rapid aging, If you cant build synapses, you cant learn and brain atrophies, In general, cells are already stressed and now they are more susceptible to death (similar to when cells choose to die rather than become cancerous by releasing, Stress plus stress is additive, especially in a short timeframe, Joe has seen it during a fight, a guy started off one way and came out different and less able to communicate later, One TBI can create damage which can continue for months after the original trauma, Multiple mild injuries can also compound this triage issue, In the brain, cholesterol is made by astrocytes and the APOE transports this to neurons, Most people have 2 APOE3 alleles (1 from each parent), 25% of people have 1 allele that is APOE4, APOE4 increases risk of Alzheimers 2-3x , TBI alone also increases risk of AD 2-3x, stroke and other neurodegenerative diseases, 2% of people have both alleles as APOE4 (from both parents), 2 APOE4 alleles increases your risk of Alzheimers by 10X, 65-80% of all Alzheimers disease have at least 1 allele of APOE4, APOE4 limits your ability to repair damage in the brain such as cleaning up amyloid beta plaque by bringing cholesterol and fatty acids to the neuron s and, In addition, APOE4 actually causes other damages itself, After damage, the brain usually increase APOE, but if you end up with more APOE4 this actually leads to even more damage, FDA recently stopped them from informing you about specific risk factors (but you can use other services to review your raw data including on, The technology has a small chance of error, so you may get a false positive, Rhonda does have 1 allele for APOE4 via her father, Fighters would be smart to get checked for risk (Joe- fighters will resist this and still want to fight, but waiting until you feel the impact, it is way too late sadly), So if you have APOE4, you REALLY need to do more sleep, This may be related to inflammation leading to the release of pro-inflammatory cytokines that cross the Blood Brain Barrier causing neural inflammation and thus aggregation of amyloid plaques, Brain inflammation in the brain also trigger, Children with autism also tend to have problems with their microbiome and inflammation in your gut which also leads to inflammation in the brain, When you cant supply this, you cant smell anymore = you lack neural stems cells which means you can no longer make new connections in the brain, Joe knows people (Gary Goodrich) who were knocked out and lost their sense of smell, Study giving young blood from mice to old mice: Can stimulate stem cells in mice and making them younger (, Found they could isolate a specific growth factor, just inject that and get same results in mice, A new study in Stanford trying this in humans people with mild AD, 76/79 NFL players whos brains were evaluated after death has significant amyloid plaque build-up, Self-directed (suicide) or towards others, If you acutely flood the brain with serotonin, you can acutely decrease impulsive behavior (2010 study) unclear this can be done for long term. Accuracy is not guaranteed. YzJkYmQxYzdmMzk3ZjI0ZmNiNDY5YjI5MWZkNWY2NWYyMjA4ZjQ5MGQxNDkx ), Include a panel of nutritionists, etc. Dr Peter McCullough appeared on a recent episode of The Joe Rogan Experience, where he claimed that health officials withheld treatments for Covid-19 in the early days of the pandemic in order. I might have to because when I actually get a chance to watch TV it doesnt happen much because right now my son falls asleep at nine and he wakes up at six. It calculates heart rate, body movement, and temperature. Rhonda Patrick is a Ph.D in biomedical science and expert on nutritional health. All notes are independently created and do not imply any sponsorship or endorsement by the source podcast. JRE #1178, #1054, #901, #773, #672, #568, #502, #459. Each teaspoon has 1600mg of Omega-3 fatty acids, so Rogan is taking in almost 5000mg of Omega-3s per day! All notes are independently created and do not imply any sponsorship or endorsement by the source podcast. NjkxYjdiZjVhNDUzM2I2Yzk1NDQ3ZDk0Nzg0MDM3ZmIwZTM4Zjc5ZDUxMDA3 Patrick: Do you? Scott Galloway joins James Altucher to discuss how COVID is changing the world, how capitalism is turning into cronyism, why telemedicine Matt Ridley joins Naval Ravikant to discuss COVID-19, filter bubbles, crypto, automation, and Tom & Tony discuss how progress is the antidote to weak culture, what fulfillment truly means, and the future of FREE when you join over 50,000 subscribers to the Podcast Notes newsletter. MTE4YzU2NzFiN2UzYTBmMGZkYjA2N2YzN2IyZjkyOThjZjE4ZDU0MzlhYTBl When Im stressed out it flares up. There is an issue between Cloudflare's cache and your origin web server. Podcast Notes isnot associated or affiliated with the source podcast (unless otherwise stated). Transcript of #1474 - Dr. Rhonda Patrick | Happy Scribe What is you just ate a bunch of organ meat to get the micronutrients youd be missing from vegetables? Patrick: Thats true. Because I know Im just going to be too stupid. #1054 - Dr. Rhonda Patrick on The Joe Rogan Experience The Joe Rogan Experience #502 - Dr. Rhonda Patrick 2014-05-16 | Dr. Rhonda Patrick is a Ph.D in biomedical science and expert on nutritional health. Patrick: Can you tell me what it is? I just dont think its totally accurate in measuring. However, if they had/possessed none of these, they had the same all cause/cancer mortality that the non-meat eaters had. ZjQ3Nzg1ZTQ4MTdlNTZlN2YzM2UwZTE5MzllYWMxMjQ2MzI0NjM1OTBlOTM5 #1701 - Dr. Rhonda Patrick - The Joe Rogan Experience | Podcast on Spotify Home Your Library Preview of Spotify Sign up free 0:00 0:00 Couldn't find that podcast Search for something else? Its really awful. Rogan: A lot of football players get it because your neck, the muscles are really big. Rogan: What are you using to monitor that?if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[250,250],'sleepline_com-leader-2','ezslot_10',662,'0','0'])};__ez_fad_position('div-gpt-ad-sleepline_com-leader-2-0'); Patrick: I dont think the sleep stage is accurate. Rhonda Perciavalle Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, Memphis TN, and St. Jude Children's Research Hospital, Memphis, TN. Healthy cells increase their stress response pathways when youre fasting (more heat shock proteins, more antioxidants etc. Joe Rogan - Dr. Rhonda Patrick on the Carnivore Diet - YouTube We may earn commission from links on this page, but we only recommend products we back. It appears to me that Dr. Patrick might not be a true physiology nerd, and I am looking for counter arguments. The first year it hit me hard because I wasnt sleeping because every three hours you have to feed the baby.if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[250,250],'sleepline_com-large-leaderboard-2','ezslot_6',659,'0','0'])};__ez_fad_position('div-gpt-ad-sleepline_com-large-leaderboard-2-0'); Rogan: Thats a giant factor in your immune system. ZDdhMjcwYThjNjNhMzA3ZTNlMzY1MThkYzI0MjI3ZjllYjQ0ZjJiZDg5NDIw ZWJmNjMxNjA3YjUzNTdiODRlZTA1N2M2OGVhMDI4ZDgzNDdhYWY2YTI3YzIw #1701 - Dr. Rhonda Patrick - The Joe Rogan Experience - Spotify They talked about the benefits of saunas on your sleep, blue light glasses, sleep apnea, and more. Before it was awful. rperciav 9 yr. ago Rhonda Patrick's Comprehensive Joe Rogan Experience Notes - FoundMyFitness Its a mouthpiece that has a tongue depressor. NTNkNWIzNzc5MWUwMjI1NjY2NTQwZGM1NDk0ZjE4NjNjNmY5ZTk2ZDdiMDFk Rogan also made the argument that people who are healthy and don't have comorbidities have suffered thrombosis and myocarditis as a result of the vaccine, but again, Patrick countered this by highlighting the comparatively low level of risk. NTEyOWJmZThjOGY3OGU5ZDEzYjc0OWVjYzQxNzUyNWRlOWVmMzA2ODY4NDM3 Previous Appearances: #1474 , #1178 , #901 Rogan: Its also great for sleep. If you believe Wordfence should be allowing you access to this site, please let them know using the steps below so they can investigate why this is happening. SHARE. Its uncomfortable, youre wearing a mask over your face. I'm a fan of Rhonda but was a bit surprised. Learn more about why you should trust our reviews and view our disclosure page. Patrick presented an argument for getting vaccinated even if you are young, healthy and active, a stance in direct opposition to the position taken by Rogan in previous episodes. Reduction of intraocular pressure for glaucoma, nausea with AIDS/Cancer, etc. About 300 different genes were different in how they were/were not activated in the sperm DNA of the obese men. Joe Rogan Supplements - What Does He Take? - Drug Genius YzQyNGQ4NzQzNmRhYTRjZjJkN2ZkMWJhZGJiOGM3ZTkzYmI3OGYwZDlmYzhi In this episode of the HVMN Podcast, Drs. -----END REPORT-----. Check out her podcast, Found My Fitness and visit her website for tons of research articles and interviews. Philip Ellis is a freelance writer and journalist from the United Kingdom covering pop culture, relationships and LGBTQ+ issues. Joe Rogan: Infrared VS Traditional Dry Sauna - YouTube One of her recent focuses is on the health impacts of saunas. Dr. Patrick has been a guest of Joe Rogan Experience ten times. YzBkYThiODBmNWY2ZjgyYWI2MTQzNTIwMTVjY2EwMDE0MTdmMzA0MWE4MjA4 Thank you Dr. Rhonda Patrick!you gave me exactly the answer I was looking for. 5 Best Joe Rogan Podcasts About Health | HealthNews EPA, DHA, cholesterol, etc. Hearst Magazine Media, Inc. All Rights Reserved. NDc0ODM1MDcwYmFmZWUwNTk3ZTcyZjgyZWNmMDliYmMzOGZhZmUwMzFjMDIz Patrick: I use melatonin. Patrick: I used to never get sick. YWU2YmU5OGZhNmU4YWU5MmU2MWZjZjdmOTBmOGVjODQxYzk5NGU1YzkwMTY3 N2YzMzY3ZjhmNTM5YTJmMmU0MWEzN2Y2MWIyZTE3NmE0YjQwNDEwOTBkYWVh Dr. Rhonda Patrick on The Joe Rogan Experience #1474 Dr. Rhonda Patrick Goes In Depth on the Benefits of Vitamin D Its amazing. MzkxOTEwODlkZjgzMTAyYmU3ZWUwZTEyM2E4Y2M3OGFjNTFhMjBhODI2M2Rh #1474 - Dr. Rhonda Patrick The Joe Rogan Experience 1,043 views 14 May 2020 Transcribe your podcast [00:00:00] Hello, friends, welcome to the show. YjBmOTYzZmEyYjhlYzI4MDFlODZjZDA2ODNkMWI2ZDk0OTI2OTE4ZDBkZjQx That makes a huge impact on my son and his sleep cycle because children are really sensitive to light because they dont have cataracts and stuff. They run our metabolism, are involved in making neurotransmitters, etc. Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Logocentrifugal Podcast With Chance Lunceford, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Jolly Swagman Podcast with Joseph Walker, The Underworld Podcast with Danny Gold and Sean Williams, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Sauna: if you have access use the sauna regularly to improve cardiovascular health and immune functions take a hot bath if you dont have access, Theres a big difference between oral vitamin C and Intravenous vitamin C, You can take vitamin C orally but will need a big dose and it still wont have the same effect; IV once per week if you can, Sleep plays a crucial role in immunity, homeostasis, and regulation of body functions, People are actively working on monoclonal antibodies, Improved therapeutic treatments coming, including more repurposing of drugs that will make things less scary, As you get older your immune system declines, There are lifestyle components of immune system you can be proactive about: exercise, sleep, supplements, nutrition, gut-microbiome health, Besides age, the major regulator of immune function seems to be previous virus exposure, not genetics, At any given point you have antibodies against 10 different viruses but youre not always getting sick, 50-80% of US population has had CMV and most people dont ever know they have had it and show no symptoms, CMV impacts immune function differently depending on when you get it, When youre young, it enhances immune response but for older people its deleterious, Interesting tie-in to COVID-19 because we know older people are more prone to severity, Its likely that theres some cross-immunity happening since SARS-COV-2 viruses is part of beta coronaviruses along with SARS-CoV-1 and MRSA, 15-30% of common colds come from coronaviruses so theres a good hypothesis that potentially one or two of common cold virus antibodies could interact with SARS-CoV-2 and neutralize it, Antibody binds to virus and instead of neutralizing it, changes the configuration so the virus can get into the cell better, This activates the immune system and causes pathology, This results in a higher viral load without antibodies to neutralize, Weve seen it happen with coronaviruses, including SARS-CoV-1 and MRSA, The spike region is where antibodies bind and is also the region the virus uses to get into the cell, Currently seeing two major strain mutations in the spike regions one mutation more prominent in Asia, one mutation more predominant in Europe and North America, Brings to light an interesting genetic link to mutations, Theres a theory that the mutation is causing peoples immune system to become more active and lead to severe COVID-19, Monoclonal antibodies: identify specific antibody that binds to spike protein and manufacture them, Problem is this will offer short lived protection since you are not making your own antibodies as you would with a vaccine, Continuous exploration into repurposing drugs and combination drug treatments, Anecdotally, the majority of people on ventilators die partly because ventilators cause more damage to the lungs and can induce more damage, But its hard to say which came first did the ventilator do the damage or was the damage so severe that the patient needed a ventilator, People with Type O blood seem to be less susceptible to contracting COVID-19, People with Type O blood create Type A antibodies which bind to spike region and neutralize antibody so it cant enter the cell, We saw this in SARS-CoV-1 so maybe same for SARS-CoV-2, Another (unproven) theory: Type O blood people have lower levels of blood factor involved in clotting, Hearing more stories that some prisoners are trying to contract SARS-CoV-2 to get out of jail by spitting in a cup and passing to others, First off, its important to distinguish between asymptomatic and pre-symptomatic, Some people do not have symptoms at the time of testing but develop symptoms later so are actually pre-symptomatic, Its possible that viruses have already gone around that environment so antibodies from those viruses are helping in immunity from SARS-CoV-2, Rhonda was also searching to literature to see whether inmates are vaccinated prior to entering but couldnt find that information, Poor sleep has a huge impact on glucose and spikes and also plays a role in maintaining optimal immune functions, Rhonda takes melatonin to help her sleep, 10 mg/day, Regulating circadian rhythm is crucial for sleep, Rhonda makes sure to have bright light exposure in the morning (e.g., opening curtains, walking outside), and changes the lighting in the house in the evening to red lights, 70% of US population has insufficient Vitamin D levels; 28% are deficient, Body can generate naturally when exposed to sun daily, Obese people in US are also more likely to be vitamin D deficient, Genetic polymorphisms: people that have variations in genes that cause them to have less vitamin D, These people are more likely to die from respiratory infection, African Americans in the US are 28x more deficient in vitamin D than Caucasians, A recent study that looked at COVID-19 patients observed an inverse relationship between vitamin D levels and COVID-19 symptoms: the lower the vitamin D levels, the higher the severity of COVID-19, In Indonesia almost all patients that died from COVID-19 were vitamin D deficient, Melanin blocks ability to produce Vitamin D, In the US and Europe, African Americans and black people are more likely to die from COVID-19, Even when adjusting for SES and lifestyle factors, this was still true so something else must be happening, Tolerable upper intake is 4000 IUs per day but its best to get vitamin D blood test to measure levels, There are clinical studies exploring the role of vitamin D but not many in the US, Rhonda wants to see nurses and first responders take vitamin D to see the role in prevention but those studies are not being done, Joe uses the sauna 7 days/week, 180-degrees for 25 min, Rhonda uses the sauna 5 days/week, 180-degrees for 25 min, Heart rate variability improves, blood pressure goes down, cardiovascular health improves, all-cause mortality decreases, Sauna use also improves immune system and makes you more resilient against infection, Brain-derived neurotropic factors (BDNF) increases with exercise and heat stress (sauna), The positive benefits of physical activity on the cardiovascular system were enhanced when sauna was added, Sauna use increases heat shock proteins which prevent muscle atrophy, neurodegenerative genes, and have anti-depressant effects, People who sat in 160-degree sauna for 30 minutes had a 60% increase in heat shock protein compared to baseline, Large Harvard study being done to assess whether hot yoga increases heat shock protein, Heat shock protein have antiviral activity against influenza A, Regular sauna is heating ambient air which in turn raises core body temperature, Infrared saunas are directly heating body without heating the ambient air for example, in a heating tent or blanket, We know more about the effects of dry sauna, For people who dont have access to sauna, a hot bath is a good modality for heat shock protein, Studies being done to assess whether sauna can have anti-depressant effect on depressed patients, Saunas could also provide an avenue for giving sedentary and disabled people the benefits of physical activity without exercising, Ice baths and cold showers can be comparable to cryotherapy but you have to stay in the cold water longer, Cold shock protein hasnt really been measured in humans, instead whats measured is norepinephrine which has been shown to increase, Cold shock protein and hot shock protein have been shown to improve mood as well, The pharmacokinetics of vitamin C are very different in oral vs IV consumption, Oral vitamin C is good for immune function, etc.