Generally, consuming it in the diet has only a small effect on antioxidant status (19). View abstract. However, these claims have limited evidence, and further research is needed. If your doctor prescribes a dosage higher than the daily value of a particular nutrient, disclose any other vitamin and herbal supplements that you take so problematic combinations can be avoided. Given that type 2 diabetes is a major risk factor for heart and vascular disease, blood sugar management is important in preventing these conditions (4, 9). Also, research on rats with diabetes given elderberry showed improved blood sugar control (4, 16, 29). These Vitamins & Supplements Might Interact With Your Birth Control, How to Help Kids with Eco-Anxiety When Fire Season Is A Thing, How to Talk to Relatives Who Dont Get Your Mental Health Needs, Real Couples Therapy Exercises That Could Help Your Relationship, turn to food for our vitamin and mineral intake, New Study Findings Highlight the High Cost of Ignoring Menopause in the Workplace, Meghan Trainor Says She Thought Every Woman Was Always in Pain During & After Sex, I Swapped Alcohol for This Adaptogen Drink & Its My Moment of Zen, How Your Vagina & Vulva Change As You Age 30s, 40s, 50s & Beyond. Elderberry can increase the activity of the immune system. Eur Cytokine Netw 2001;12:290-6.. View abstract. J Int Med Res. Signs that you are still dealing with copper deficiency include fatigue, weakness, brittle bones, cold sensitivity and easy bruising. The common side effects of taking raw elderberry plant products, such as fruit, flower, leaves, bark, or root include: Stomach problems. Jennifer Lefton, MS, RD/N-AP, CNSC, FAND is a Registered Dietitian/Nutritionist and writer with over 20 year of experience in clinical nutrition. Here are six vitamin combinations you definitely shouldnt take together. The phase IV clinical study analyzes what interactions people who take Elderberry and Vitamin c have. This can happen out of the blue, often after you have been taking CoQ10 for six to eight weeks, and it could precipitate a fall or head injury. Watch out for these other symptoms of low blood pressure. While both of these B vitamins are important, taking too much folic acid or folate can actually hide the symptoms of a vitamin B12 deficiency. Elderberry use is considered safe for up to 12 weeks. This is particularly important to keep in mind for those taking blood thinning medications, such as warfarin. Kunitz S, Melton RJ, Updyke T, et al. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. In some clinical trials, adults took 3 teaspoons (1 tablespoon) of elderberry extract in syrup form four times daily for five days. Constipation. View abstract. Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food a review. View abstract. Vitamin B12 plays an important role in red blood cell production and the proper functioning of your nervous system, and B12 deficiency can lead to poorer nerve health and affect red blood cell development and function., While the mixing of supplements can be overwhelming at first, Stokes says the most important aspect of a supplement regimen is to keep it simple, to set yourself up for success. MedicineNet does not provide medical advice, diagnosis or treatment. Part of the reason behind the confusion is for some supplements, your absorption level can depend on which ones you are taking together and may also result in adverse interactions, which can be harmful to your health. Elderberry may have positive effects on some markers of heart and blood vessel health. All Rights Reserved. Clin Exp Allergy 2003;33:1703-10. Once standards are available, supplement companies can be held accountable for providing high-quality products. All information is observation-only. Elderberry juice syrup has been used for centuries as a home remedy for viral illnesses like the common cold and flu. At the same time, some vitamins interact with medications in potentially harmful ways. What Happens If I Take Too Much Elderberry? Furthermore, elderberries may reduce levels of uric acid in the blood. This tree is native to Europe, though it is widely grown in many other parts of the world as well (1, 2). Many high-quality multivitamins, such as those that are "food based," may also require more than one dose in order to help you absorb more of the nutrients. Ac., CYT, the evidence supporting its health claims. There is no defined, standard dose of elderberry, so the amounts given differ among studies. Elderberry fruits, leaves, and flowers are strong antioxidants. You can give your kids a small daily dose of elderberry during cold and flu season to strengthen their immune system. It is created by eHealthMe based on reports of 74 people who take Vitamin d and Elderberry from the FDA, and is updated regularly. It is based on american elder and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Elderberry and Multivitamin, respectively), and Elderberry and Multivitamin (the brand names). Elderberry is associated with many additional health benefits, such as fighting cancer and bacteria, immune support, UV protection, and diuretic effects. Taking a multivitamin that includes niacin, or vitamin B3, is typically safe in combination with other nutrients. Can I Take a Multivitamin If I'm on B12 Pills? Clin Chem 1999;45:574-6. Some researchers have suggested that the syrup shortens the duration of some illnesses and makes them less severe; however, the study findings have varied. Another study in rats found that elderberry extract helped reduce inflammation and oxidative tissue damage (20, 21). She has received numerous awards, including the Arthritis Foundation's Northeast Region Prize for Online Journalism; the Excellence in Women's Health Research Journalism Award; the Journalistic Achievement Award from the American Society for Aesthetic Plastic Surgery; National Newsmaker of the Year by the Community Anti-Drug Coalitions of America; the Gold Award for Best Service Journalism from the Magazine Association of the Southeast; a Bronze Award from The American Society of Healthcare Publication Editors (for a cover story she wrote in, We are no longer supporting IE (Internet Explorer), x things you should know before you begin taking magnesium supplements, vitamins are a waste of money and could even be dangerous, more things to know if you are going to take melatonin, nutrients even nutritionists dont get enough of, signs your body is running low on key vitamins, super-important questions to ask before you take prescription medications, foods you shouldnt eat with certain medications, these vitamin mistakes you might not know youre making, Do not Sell or Share My Personal Information. It is most often taken as a supplement to treat cold and flu symptoms. pii: E182. Which vitamins are best paired and recommended to be taken together? Vitamin K plays a critical role in your body's ability to properly clot your blood. So, speak to your doctor to verify your vitamin levels before adding these supplements to your regimen. The uncooked berries, leaves, bark, and roots of the elderberry plant contain the chemicals lectin and cyanide, which can cause nausea, vomiting, and diarrhea. Almost 70% of older adults use them. Zakay-Rones Z, Thom E, Wollan T, Wadstein J. Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. Symptoms of eating uncooked berries, leaves, bark, or roots of the elderberry include nausea, vomiting, and diarrhea (2). 2020 Sep 14. doi: 10.1007/s11606-020-06170-w. View abstract. Elderberry, meanwhile, contains tons of antioxidants called flavonoidsalong with vitamin A, B . View abstract. Its OK to drink green tea beveragessuch as matchajust dont do it with your iron supplements, Dr. Cooperman says; spread the two apart by a couple of hours. Cyanogenic glycoside analysis in American elderberry. Elderberry & Echinacea. Some vitamins and supplements can interfere with blood-thinning blood pressure drugs, Dr. Glatter says. Report any adverse supplement reactions to the FDA. This article will review the potential uses of elderberry, how to safely use it, and possible concerns with using elderberry. Our Nature Made Elderberry Gummies with Vitamin C & Zinc and Elderberry Syrup with Vitamin C & Zinc can be taken daily, as long as they are taken within the recommended daily dosage for adults and children. J Diet Suppl. Taking large amounts of folate can correct the anemia, making you think that you are good to go. Taking antibioticsespecially those in the tetracycline familyalong with iron supplements can dampen the effects of the antibiotics, making them less likely to work, Dr. Glatter says. Vitamin C and B12. Dr. Glatter warns that CoQ10 can also lower blood sugar, and if you are taking other diabetes drugs, you run the risk of developing low blood sugar, he says. Skip green tea on days when youre taking your iron supplement and decrease your weekly consumption. You may have side effects when combining certain supplements with antidepressants and anti-anxiety medications. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. Multivitamins typically include all of these 13 essential nutrients. The major elderberry (Sambucus nigra) fruit protein is a lectin derived from a truncated type 2 ribosome-inactivating protein. There is one report of eight people falling ill after drinking the juice from freshly picked berries, including the leaves and branches, from the S. mexicana elder variety. 2019;42:361365. View abstract. The study uses data from the FDA. Read more: How to Determine if a Vitamin or Supplement Is Actually Right for You. Macknin M, Wolski K, Negrey J, Mace S. Elderberry extract outpatient influenza treatment for emergency room patients ages 5 and above: a randomized, double-blind, placebo-controlled trial. Next, be sure to check out these vitamin mistakes you might not know youre making. 2012;33:204-11. Thank you, {{form.email}}, for signing up. The phase IV clinical study analyzes what interactions people who take Elderberry and Multivitamin have. Bitsch I, Janssen M, Netzel M, et al. There isn't enough reliable information to know if it is safe to use for longer than 12 weeks. Van Damme EJ, Roy S, Barre A, et al. Elderberries, raw. 2017;72(1):82-7. Despite these promising results, a direct reduction in heart attacks or other symptoms of heart disease has not yet been demonstrated, and further studies in humans are needed. Follow these tips to stay safe with supplements. It can cause bleeding episodes after a fall or injury, and theres a high risk of internal bleeding, he says. 2014;11(1):80-120. doi:10.3109/19390211.2013.859852. Some participants also took. One source of zinc supplementation is denture cream. J Altern Complement Med 1995;1:361-9. Verywell Health's content is for informational and educational purposes only. Elderberry has been shown to reduce symptoms of the flu. All rights reserved. B vitamins can be taken together (and may be combined into a "B complex" supplement). The most common type is Sambucus nigra, also known as European elderberry or black elderberry. In addition to treating colds and the flu, people have turned to elderberry supplements to treat: Chronic fatigue syndrome. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Giannattasio A, Poggi E, Trapani G, et al. What is elderberry used for? Elderberry With Vitamin C and Zinc: Does It Work? This is just 3% of the estimated fatal dose for a 130-pound (60-kg) person (2, 35). These foods are so high in vitamin A that even if you do not take a vitamin A supplement, you should only eat them once a week to avoid consuming too much. Nausea and vomiting. It has many health benefits, and may help protect against several chronic conditions. The heart benefits seem strongest when eating fatty fish twice a week. A caveat: This interaction has only been studied in those who currently have coronary artery disease (CAD). J Int Med Res 2004;32:132-40. Online Journal of Pharmacology and Pharmacokinetics 2009;5:32-43. J Funct Foods. 1996-2023 MedicineNet, Inc. An Internet Brands company. By using this site you agree to our Privacy Policy. For example, St. Johns wort may cause fever, confusion, and anxiety if its taken with other antidepressants. You may feel numbness or tingling in your extremities. The solution? Kirichenko TV, Sobenin IA, Markina YV, et al. Cooked elderberry fruit is safe, but raw elderberry may cause nausea, vomiting, or severe diarrhea. Dietary supplements vary widely when it comes to the nutrients they provide, as well as the dosage of those nutrients. Elderberry Gummies Elderberry gummies combine the best natural antioxidants in a single supplement. Cathy Wong is a nutritionist and wellness expert. Garlic thins out the blood, and if you take a daily baby aspirin or a blood thinner such as Coumadin (warfarin), it could be risky, Dr. Glatter says. Your body depends on magnesium to allow it to absorb vitamin D. Enzymes in your liver and kidneys need magnesium to break down the vitamin and convert it into a form your body can work with. Some herbal remedies can also interact with the blood thinner warfarin (Coumadin) including: High doses of vitamin D can interact poorly with drugs to lower cholesterol and blood pressure, as well as some other drugs used to treat heart disease. An evidence-based systematic review of elderberry and elderflower (Sambucus nigra) by the Natural Standard Research Collaboration. If you opt to take multivitamins, the Mayo Clinic recommends choosing one that provides no more than 100 percent of the daily value of each nutrient. However, commercial preparations and cooked berries do not contain cyanide, so there are no reports of fatalities from eating these. Elderberry (Sambucus species). Best Ways to Take Different Vitamins - WebMD Some doctors prescribe a vitamin K supplement to help with blood clotting. For example, one of the anthocyanins found in the berries has 3.5 times the antioxidant power of vitamin E (4, 15, 16, 17). In fact, vitamin E supplementation of over 800 IU can interfere with blood clotting and make your blood thinner. View abstract. That said, there is no benefit to taking elderberry every day, as it does not prevent illness. Green tea has anti-inflammatory compounds that may help people with conditions like inflammatory bowel disease. Always tell your doctor about all supplements you take before any surgery or procedure. There is no data evaluating elderberry safety in people who are pregnant or breastfeeding. Since the effects of grapefruit juice may last as long as 3 days, it should be avoided if you are taking atorvastatin (Lipitor), lovastatin (Mevacor, Altoprev) or simvastatin (Zocor). And, while we should always turn to food for our vitamin and mineral intake, sometimes vitamin supplementation can help us fill the gaps in our diet. In fact, the Council for Responsible Nutrition estimates that 3 out of 4 Americans are regularly taking a vitamin or other dietary add-on. Many people take them to help prevent or treat colds. Before you embark on any supplement regimen, I suggest you ask a holistic-minded practitioner what is right for you with consideration to your allergies, your liver, kidney function and even genetic mutations.. By learning all you can about vitamins and minerals you . Its never safe to eat unknown berries in nature, as they may have dangerous effects. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. The phase IV clinical study analyzes what interactions people who take Vitamin d and Elderberry have. Elderberry and COVID-19: What You Need to Know - Healthline But one rule remains the samethe most important time to take a vitamin pill is a time you will remember day after day. Doubling up doesnt increase the benefits and may be harmful to the liver, says Todd SontagDO, a family medicine specialist with Orlando Health Physician Associates in Florida. Inflammatory cytokines, An evidence-based systematic review of elderberry and elderflower (, Chemical profiling and UHPLC-QToF analysis for the simultaneous determination of anthocyanins and flavonoids in Sambucus berries and authentication and detection of adulteration in elderberry dietary supplements using UHPLC-PDA-MS, 2021 US open forum: elderberry standards development, A 2020 study did not find black elderberry to improve symptoms or reduce the amount of time of illness. Can You Take Elderberry Daily? - Nature Made They complement the elderberry extract with additional vitamin C and zinc for enhanced immunity. Maximize your benefits by taking any mineral supplements at least two hours apart. Can You Take Probiotics When You Take Vitamins Or Supplements While omega-3 fish oil supplements are great for heart health and gingko biloba can be used to aid cognitive impairment, according to Dr. Tripathy, both have blood-thinning potentials and taking both together can increase risk for uncontrollable bleeding or inability to clot., If you are taking copper supplements because of copper deficiency, avoid taking zinc at the same time, says Dr. Airey. If your doctor recommends a vitamin K supplement, avoid taking high dosages of vitamin E, which may counteract the effects of vitamin K, according to MedlinePlus. Its advised that you take these vitamins at least 2 hours apart to maximize your absorption.. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Effect of an herbal mouth rinse in preventing periodontal inflammation in an experimental gingivitis model: a pilot study. 2023 UAB Health System. Sciatica. Be sure to take vitamin C at least two hours after vitamin B-12. There are many other reported benefits of elderberry, though most of these have limited scientific evidence: While these results are interesting, further research is needed in humans to determine if the effects are truly significant. Barak V, Halperin T, Kalickman I. During normal metabolism, reactive molecules may be released that can accumulate in the body. However, no large clinical studies have proven these benefits. Vitamins and Supplements That Should Not Be Taken Together - Health Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. Whether or not they are effective, they are usually safe to take. Shutterstock (2) Potassium and calcium Taking large amounts of minerals with other minerals will reduce absorption, he says. Both vitamin C and zinc are essential for the body for protection from covid-19 or coronavirus. Its still gathered and used in folk medicine across many parts of Europe. 2020;35(11):3271-3277. doi:10.1007/s11606-020-06170-w, Hawkins J, Baker C, Cherry L, Dunne E. Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Just because something is natural doesnt mean it is risk-free. Garlic isnt the only supplement that can up your bleeding risk. View abstract. However, further research is needed to demonstrate if these effects are significant in humans. An observational study and quantification of the actives in a supplement with Sambucus nigra and Asparagus officinalis used for weight reduction. Deficiencies in either can cause extreme exhaustion. Keep your supplements stored according to the instructions on the product label. Available at: https://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009). Plus, they have many nutritional benefits. One cup of elderberries provides 106 calories, 27 grams (g) of carbohydrates, 10 g of fiber, 52 milligrams (mg) of vitamin C, 2.3 mg of iron, and 406 mg of potassium. Since there is no recommended dosage, follow the instructions on the product label or ask your provider how much you should use. Terms of Use. Elderberry extract has been found to help reduce the length and severity of symptoms caused by the influenza virus. Also, be sure to remove any bark or leaves before use. In their uncooked state, elderberries are toxic and can cause diarrhea, vomiting and nausea. In the United States, supplements are not regulated by the Food and Drug Administration. Here are some more things to know if you are going to take melatonin. View abstract. Iron is found in meat, beans, and leafy green vegetables. Again, these necessary minerals will compete for absorption by the body, meaning you get less of each when you take them together, warns Dr. Cooperman. The mealtime rule also goes for multivitamins and prenatal preparations. 2014 Summer;13(3):1003-9. Headaches. The problem? Copper helps with brain development, nervous system health, and in making important tissues in the body. View abstract. Studies have shown elderberry juice may reduce the level of fat in the blood and decrease cholesterol. Biology (Basel). Here are the 7 best elderberry gummies. Our website services, content, and products are for informational purposes only. It is a rich source of antioxidants known as anthocyanins and is often used to support the immune system. Compend.Contin.Educ.Dent. They're naturally flavored with. Some individuals should avoid certain combinations of dietary supplements. Frank T, Janssen M, Netzet G, Christian B, Bitsch I, Netzel M. Absorption and excretion of elderberry (Sambucus nigra L.) anthocyanins in healthy humans. Toothaches. Featuring vitamin C, zinc, and 50 mg of black elderberry extract per serving, these gummies are a great option for adults looking for extra immune support. Personalize this study to your gender and age, Propranolol Hydrochloride vs. Escitalopram Oxalate, Fludrocortisone Acetate and Bromocriptine Mesylate drug interaction, Simvastatin and Dasatinib drug interaction.