ACG clinical guideline: treatment of Helicobacter pylori infection. Drug information provided by: Merative, Micromedex. The most common side effects that can occur while taking metronidazole tablets or capsules include: Serious side effects can occur while taking metronidazole tablets or capsules. If you have any of these side effects, stop taking metronidazole right away and call your doctor. Some birth control methods like IUDs or implants that release progestin can cause spotting, irregular menstruation, and brown discharge. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Swallow the extended-release tablets whole; do not split, chew, or crush them. Treatment of noninfectious vaginitis should be directed at the underlying cause. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. It's been 5 days and I am still having the discharge. health information, we will treat all of that information as protected health Metronidazole (Oral Route) Side Effects - Mayo Clinic This is the most serious warning from the Food and Drug Administration (FDA). Sometimes a discharge is . Doctors typically provide answers within 24 hours. Generic drugs usually cost less than the brand-name version. Culture can be helpful for the diagnosis of complicated vulvovaginal candidiasis by identifying nonalbicans strains of Candida. Bacterial vaginosis is traditionally diagnosed with Amsel criteria, although Gram stain is the diagnostic standard. Brown discharge at other points in your cycle may still be normal but be sure to take note of any other symptoms you experience. Studies have shown a negative effect on quality of life in women with vaginitis, with some women expressing anxiety, shame, and concerns about hygiene, particularly in those with recurrent symptoms.38. This is more likely with birth control methods that contain little to no estrogen as a lack of estrogen can cause the lining of the uterus to shed a little at a time. In some cases, you may not experience any symptoms with these infections. Type: Rx Drug METROGEL-VAGINAL (METRONIDAZOLE): This medication is used to treat certain types of bacterial infections in the vagina. Ive had recurring yeast infection. This condition causes the skin of your face to redden and form small bumps. How to treat it: Spotting due to hormonal contraception is not usually a cause for concern and should go away about three months after having an IUD implanted or starting a low-estrogen birth control pill. If you stop taking this medication too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. Seizures: If you have a history of seizures, be sure to tell your doctor before starting metronidazole tablets or capsules. Go back and see your gynecologist. If youre near your menstrual cycle or youre just done with it, the drug discharge could simply be old blood. It is extremely important that people who take Flagyl not drink alcoholic beverages until at least 3 days after stopping the drug. Nitroimidazole antimicrobials treat infections caused by bacteria and other organisms called protozoa. Vulvovaginal candidiasis can be diagnosed by visualization of yeast hyphae on potassium hydroxide preparation (Figure 214 ) in a woman with typical symptoms. Do you have suggestions for ways to prevent or reduce side effects. Newer laboratory tests such as DNA and antigen testing for bacterial vaginosis and vulvovaginal candidiasis, or vaginal fluid sialidase testing for bacterial vaginosis, may have similar or better sensitivity and specificity compared with traditional office-based testing. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. Review article: the pathogenesis of pouchitis. Page last updated: 11/18/2022 |, Next review date: 11/18/2024. Urinary tract infections (UTIs) can usually be treated with antibiotics, but there are times when the drugs are unable to fully clear the infection. Each form has different side effects. The generic name for this antibiotic is metronidazole, and it also may be sold under names such as Metrogel, Metrolotion, Noritate, Nuvessa, and Vandazole. In some cases, brown discharge can be a sign of a health condition that needs medical treatment, including an STI, pelvic inflammatory disease, or cancer. You should avoid items with alcohol while using metronidazole and for three days after you finish treatment. Early miscarriage could also cause these symptoms. Stevens-Johnson syndrome, Metrocream - metronidazole cream. Treatment of bacterial vaginosis is recommended for resolving symptoms, as well as reducing the risk of Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, human immunodeficiency virus (HIV), and herpes simplex virus type 2 infections.37 Shifts in vaginal flora have been associated with increased risk of these infections, leading researchers to conclude that treatment of bacterial vaginosis may decrease susceptibility to these infections.38,39, First-line therapy includes seven-day courses of oral metronidazole (Flagyl), intravaginal metronidazole (Metrogel), or intravaginal clindamycin.9 No significant difference in effectiveness has been demonstrated among these regimens.40 Patient preference should be considered when choosing an agent. These include infections that occur in the gastrointestinal tract or reproductive systems such as amebiasis and trichomoniasis. Data are insufficient on the safety of secnidazole use in pregnancy, and use is not recommended with breastfeeding.43, Bacterial Vaginosis in Pregnancy. There is no odor. Some data show that newer laboratory tests such as DNA and antigen testing for bacterial vaginosis and vulvovaginal candidiasis, or vaginal fluid sialidase testing for bacterial vaginosis, may have similar or better sensitivity and specificity compared with office-based testing.33 However, more comparisons with diagnostic standard testing (i.e., Gram stain for bacterial vaginosis and culture for vulvovaginal candidiasis) are needed. We comply with the HONcode standard for trustworthy health information. Im on flagyl for bv but having some red brown discharge. Healthline Media does not provide medical advice, diagnosis, or treatment. Here is a look at how this happens and, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Routine testing in asymptomatic women and retesting (test of cure) are not recommended because these bacteria can be part of normal flora. Patients should be instructed to insert the swab at least one inch into the vagina. If you're still experiencing these symptoms maybe you should get a second opinion, but don't worry if the discharge happens while you're taking metro gel, it's a common side effect. Is brown discharge after taking Metronidazole normal? Another possibility of such discharge is the concomitant use of Metronidazole with birth control pills. If your vaginal discharge is red or brown. Still looking for answers? Metronidazole Side Effects: Capsules, Gel, Alcohol, and More - Healthline I was taking metronidazole for 5 days now i have a thick dark brown clumpy discharge i was also told i might have hpv is this normal or should i be? Stevens-Johnson syndrome: Stevens-Johnson syndrome is a rare but serious skin disorder. What Causes Painful Menstrual Periods and How Do I Treat Them? How to treat it: Treatment for uterine fibroids can vary depending on your health history and the severity of your fibroids and symptoms. Schieffer KM, Williams ED, Yochum GS, Koltun WA. a few days ago it seemed like the symptoms were clearing but now it hurts when i go to the toilet and it hurts down below too? The amount of vaginal discharge can vary significantly from person to person. However, in some cases, brown discharge can be old blood thats taking extra time to leave the uterus. Metronidazole topical cream, lotion, and gel treat inflammation caused by rosacea. In nonpregnant patients, there is no definitive advantage of one treatment over another in terms of clinical or mycologic cure, with all treatment options having about an 80% cure rate.47,48 Limited data demonstrate that patients may prefer oral regimens.4951, There are several considerations when choosing between topical and oral treatment.52,53 Topical preparations may provide more immediate relief because of the soothing nature of topical treatment or, conversely, may cause local hypersensitivity reactions resulting in itching or burning. Although not all of these side effects may occur, if they do occur they may need medical attention. If you have trouble breathing, call 911. For these, please consult a doctor (virtually or in person). H. pylori infects the stomach and can lead to stomach ulcers. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. See permissionsforcopyrightquestions and/or permission requests. Metronidazole extended-release (long-acting . How to treat it: PID can be treated with antibiotics, but the potential damage the disease can do to your reproductive organs can not be reversed. Other signs of endometrial cancer include: Brown discharge is a less prevalent sign of cervical cancer but can occur, Kimble says. How to treat it: Both chlamydia and gonorrhea are treated with antibiotics, which can clear the infection within a couple weeks. This content does not have an English version. still have bad odor? Menopause-related changes. They can include: Serious side effects of the vaginal gel are rare. Common metronidazole side effects may include: depression, trouble sleeping, feeling irritable; headache, dizziness, weakness; nausea, vomiting, loss of appetite, stomach pain; diarrhea, constipation; unpleasant metallic taste; rash, itching; vaginal itching or discharge, pain during sex; mouth sores; or swollen, red, or "hairy" tongue. Systemic estrogen therapies are also available for patients with vasomotor symptoms.67 First-line nonhormonal treatment recommendations include vaginal lubricants and moisturizers; continued sexual activity should be encouraged.68, More research is needed to better characterize the cause and treatment of inflammatory vaginitis. All antibiotics can reduce the effectiveness of oral contraceptives (the pill), so women using this as their birth control method should use a backup method until after finishing the course of antibiotics. Metronidazole may be used as part of combination therapy. Ive had recurring yeast infection. Even if it is milder, Dr. Andrew Seibert and another doctor agree. 2016;44(8):817-835. doi:10.1111/apt.13780, Chey WD, Leontiadis GI, Howden CW, Moss SF. The most common causes of vaginitis are bacterial vaginosis, vulvovaginal candidiasis, and trichomoniasis. To provide you with the most relevant and helpful information, and understand which Erin Heger is a freelance journalist located in the Kansas City area. And you can decrease your risk of endometrial cancer by maintaining a healthy lifestyle of regular exercise and a nutritional diet. Using condoms can also reduce the risk of contracting an STI or passing the infection on to someone else. prescribed metronidazole. finishing flagyl tonight. Lets discuss the details. These side effects can include yeast infection and the following skin effects: The topical gel may also cause these additional side effects: Metronidazole vaginal gel treats bacterial vaginosis. turning from a red color to a more brown hue, normal and not typically a cause for concern, cause spotting, irregular menstruation, and brown discharge, infection of the human reproductive organs, The 4 phases of the menstrual cycle and why your cycle could be irregular, Why you should track your period and the best ways to do it, 9 reasons why you may be spotting, from stress to PCOS, 3 ways to treat a yeast infection at home. Metronidazole is an antibiotic that works by stopping the growth of bacteria. Surgery to remove the fibroids. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, What Happens When Bacteria Become Resistant to Antibiotics, New Drug Candidate May Be Effective Against 300 Drug-Resistant Bacteria, Does Your Child Really Need that Antibiotic? Cancer. The Centers for Disease Control and Prevention recommends nucleic acid amplification testing for the diagnosis of trichomoniasis in symptomatic or high-risk women. To get you started, try asking these questions: Together, you and your doctor can help you treat your infection as safely as possible. It can also be a sign of certain STIs like chlamydia and gonorrhea or pelvic inflammatory disease. The most common causes of vaginitis are bacterial vaginosis, vulvovaginal candidiasis, and trichomoniasis. Missing an "active" bcp (not a placebo) will start withdrawal bleeding from the lowered estrogen level effect on the lining of the uterus. How long during treatment of bv does it take for discharge to go away odor gone but still some discharge? Try searching for what you seek or ask your own question. Get a followip appt. Flagyl is also used to treat an infection in the digestive tract with a bacteria called Clostridioides difficile(formerly called Clostridium difficile, commonly called C. diff). After using metronidazole gel when will the chunky white discharge Metronidazole capsules and tablets are usually taken as a one-time dose (or divided into two doses on 1 day) or two to four times daily for up to 10 days or longer. Although Gram stain is considered the diagnostic standard, bacterial vaginosis is traditionally diagnosed using the Amsel criteria (Table 3).14,23 Criteria include thin, homogenous discharge; a positive whiff test; the presence of clue cells on microscopy (Figure 114 ); and a vaginal pH greater than 4.5. Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. Might have developed a yeast infection. FLAGYL- metronidazole capsule. Check with your doctor to undergo thorough evaluation and find the real cause. Learn how we can help. Flagyl affects the way alcohol is broken down, and that leads to symptoms of nausea and vomiting, which can be severe. The brown thick discharge after taking metronidazole will usually go away after you complete the full course of metronidazole treatment. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. UpToDate It's normal to have discharge every day. Do not take more or less of it or take it more often than prescribed by your doctor. Why is metronidazole gel causing thick chunky white discharge? She explains. Metronidazole (Uses, Dosage, Side Effects) - Drugs.com Copyright: Merative US L.P. 1973, 2023. First-line and alternative treatment regimens for vaginitis are presented in Table 4 with suggestions for recurrent infection, treatment during pregnancy, and treatment of sex partners.9,16 Additional considerations for the treatment of bacterial vaginosis, vulvovaginal candidiasis, and trichomoniasis are discussed. There is no cause of vaginitis identified in up to 30% of women. Trichomoniasis is treated with oral metronidazole or tinidazole, and patients' sex partners should be treated as well. If a UTI comes back right after taking an antibiotic, it may be due to problems with how the drugs were taken. If we combine this information with your protected Further review of the evidence has demonstrated that antibiotic treatment does not prevent preterm birth for women with symptomatic or asymptomatic bacterial vaginosis.44,45 Although a previous meta-analysis demonstrated a possible reduction in preterm labor with treatment of bacterial vaginosis, particularly in early pregnancy (before 20 weeks' gestation),46 a more recent meta-analysis of 21 studies found that antibiotic treatmentregardless of route of administration (oral or topical), the timing in pregnancy, or history of preterm labor in previous pregnanciesdoes not prevent preterm birth for women with symptomatic or asymptomatic bacterial vaginosis.45 Two studies cited in this meta-analysis that included the presence of abnormal vaginal flora as well as bacterial vaginosis showed a possible reduction in preterm labor before 37 weeks' gestation with treatment; therefore, further investigation may provide more information about the role of abnormal bacterial flora and its treatment in pregnancy.45 Regardless, treatment of bacterial vaginosis is generally recommended for symptomatic relief, and adverse effects of metronidazole in pregnancy have not been demonstrated.45, Treatment of candidal infection is aimed at reducing symptoms. privacy practices. For potential or actual medical emergencies, immediately call 911 or your local emergency service. Top answers from doctors based on your search: Created for people with ongoing healthcare needs but benefits everyone. "If I'm still experiencing a discharge after being treated for b.v Mayo Clinic does not endorse companies or products. Vaginal culture also has a high sensitivity for identifying Trichomonas, but it has largely been replaced by nucleic acid amplification testing because of the longer time (up to one week) needed for results.9, Because trichomoniasis is sexually transmitted and has a high rate of recurrence, the CDC recommends testing for reinfection three months after treatment.9. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. If you have flu-like symptoms, call your doctor. Not uncommon for the infection to return shortly. Her work been featured in TheAtlantic, Rewire.News, Refinery29, HuffPost, and more. Vaginal discharge is fluid secreted from tiny glands in the vagina and cervix. Why You Have UTI Symptoms After Taking Antibiotics - Verywell Health Bacterial vaginosis is the cause in 40% to 50% of cases in which a cause is identified, with vulvovaginal candidiasis accounting for 20% to 25% and trichomoniasis for 15% to 20% of cases. Symptoms can appear in this order: Stevens-Johnson syndrome is a medical emergency. Yo - it may need to be treated before it resolves. Available for Android and iOS devices. There is a problem with (2013, October 17), Side effects of topical cream, gel, and lotion, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a2883ca1-5a9a-4259-9d80-46ab67274384, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b39cc0e4-57ad-4d70-a105-44ebccf201f8, mayoclinic.org/diseases-conditions/stevens-johnson-syndrome/basics/definition/con-20029623?p=1, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=43d5e570-f359-564d-9bb4-51784ad97b6f, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ab3a8a2d-714a-4beb-af8a-99bc3ac3ebbe, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c4e07c26-245d-3e51-6a47-fccde22334d2, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2ede12d7-421c-4580-93ad-289a5c616297, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=520c3783-b0fa-407b-8c4a-3830af32b8fa, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=706b09da-6cf9-421d-8e91-f3999474d322, labeling.pfizer.com/showlabeling.aspx?id=572, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=27d71471-8f89-4a1e-8c55-020a58961454, Bad Buzz: Metronidazole (Flagyl) and Alcohol. Is there another medication I could take that might have fewer side effects? Other side effects not listed above may also occur in some patients. Dr. Jane Van Dis answered Obstetrics and Gynecology 20 years experience Usually 2-3 days: 2-3 days after treatment begins, the odor should start to go away. FLAGYL- metronidazole tablet, film coated [drug label]. forms. Am J Gastroenterol. Question posted by sydneyburns on 9 Nov 2014, Last updated on 21 December 2014 by SHEsevEN4. Do not stop taking it without talking to your doctor. Metronidazole is an antimicrobial that has been used to treat infections. Flagyl is a type of antibiotic and an antiprotozoal medication that is used to treat bacterial infections in the body. This content is owned by the AAFP. Antibiotics can both cause infections that may lead to pancreatitis, but they are also used in their treatment. Infections with nonalbicans species are less responsive to fluconazole. All rights reserved. However, studies have shown that, regardless of whether they have a history of vulvovaginal candidiasis, women are not able to accurately self-diagnose the condition, often using these products for causes of vaginitis other than candidal infections.54, Vulvovaginal Candidiasis in Pregnancy. Sometimes a discharge is Metronidazole is frequently used for gardnerella vaginal infections (a frequent cause for bacterial vaginosis). To learn more, please visit our. In fact, the most common sign of endometrial cancer is blood in your discharge and unusual vaginal bleeding. Slimy brown discharge and bad odor after bv treatment. There may be a similar risk for cancer in humans. Brown discharge could also indicate infection or other conditions, such as breakthrough bleeding with your birth control method, a retained tampon or piece of condom, polyps and fibroids, and very rarely cervix or uterine cancer. It is available in oral, rectal, topical, vaginal and intravenous (I.V.) Is this normal? Metronidazole is a prescription drug used to treat infections caused by bacteria or other parasites in different parts of your body. A couple of days: When taking metrogel, a vaginal antibiotic to treat bacterial vaginosis, it commonly causes an odd discharge from the vagina. Vaginitis: Diagnosis and Treatment | AAFP Is Brown Discharge After Taking Misoprostol Normal? Metronidazole comes as a tablet, an extended-release tablet, and as a capsule to take by mouth. Most people experience mild pain. It may lead to pain with urination or intercourse. See a primary care physician or OB/GYN BV often has few symptoms besides a fishy odor. It's usually the result of the vagina cleaning itself to prevent infections. Is Brown Discharge After Taking Metronidazole Normal? The information on this site is for informational and educational purposes only. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. thick, white vaginal discharge with no odor or with a mild odor Less common Burning on urination or need to urinate more often burning or irritation of the penis of the sexual partner feeling of vaginal pressure itching, pain, stinging, or redness of the genital area Some side effects may occur that usually do not need medical attention. thank you! No pain or itching around the vagina. This antibiotic is used to treat infections and pouchitis in j-pouches. Metronidazole thick discharge | HealthTap Online Doctor No studies were found on the cost-effectiveness of these newer tests compared with office-based testing. Recurrent yeast suggests you have intestinal yeast overgrow "Borderline" BV probably is real BV, and metronidazole orally almost always is effective. I take birth control, missed 2 days, brown discharge started yesterday. When clue cells or hyphae are present on a Pap test, treatment depends on symptoms. Vulvovaginal candidiasis is common during pregnancy. Seek medical care If your brown discharge is accompanied by other signs of cervical cancer, including: How to treat it: Treatment for cervical or endometrial cancer can vary depending on the progression of the disease and your health history. For patients with severe vulvovaginal candidiasis, a second dose of fluconazole given three days after the first dose has been shown to achieve significant improvement in short-term symptoms as well as prevent recurrence at 35 days. Noninfectious causes, including atrophic, irritant, allergic, and inflammatory vaginitis, are less common and account for 5% to 10% of vaginitis cases.9, The history alone is unreliable for the diagnosis of different causes of vaginitis.10 Physical examination findings and office-based or laboratory test results should be used with the history to determine the diagnosis.1113 Characteristic clinical signs and symptoms for different causes of vaginitis are listed in Table 1.10,14,15 Risk factors for vaginitis are listed in Table 2.9,14,16. Your discharge is not a normal effect of metronidazole. Flagyl may be used to treat infections occurring in the skin, reproductive organs, and the digestive tract. All topical treatments listed in Table 5,9,16 as well as oral fluconazole, are recommended by the CDC as first-line therapy for vulvovaginal candidiasis.9 The choice of treatment should be made in conjunction with patient preference and previous experience with these agents. Fishy odor; thin, homogenous discharge that may worsen after intercourse; pelvic discomfort may be present, Increased risk of HIV, gonorrhea, chlamydia, and herpes infections, White, thick, cheesy, or curdy discharge; vulvar itching or burning; no odor, Green or yellow, frothy discharge; foul odor; vaginal pain or soreness, Thin, clear discharge; vaginal dryness; dyspareunia; itching, Inflammation; thin, friable vaginal mucosa, Purulent vaginal discharge, burning, dyspareunia, Low socioeconomic status, vaginal douching, smoking, new or multiple sex partners, unprotected intercourse, women who have sex with women, Recent antibiotic use, pregnancy, uncontrolled diabetes mellitus, AIDS, corticosteroid use, other immunosuppression, Low socioeconomic status, multiple sex partners, other sexually transmitted infections, unprotected intercourse, drug use, smoking, Menopause, lactation, oophorectomy, radiation therapy, chemotherapy, immunologic disorders, premature ovarian failure, endocrine disorders, antiestrogen medications, Soaps, tampons, contraceptive devices such as condoms or diaphragms, sex toys, pessaries, topical products, douching, fastidious cleansing, medications, clothing, Sperm, douching, latex condoms or diaphragms, tampons, topical products, medications, clothing, atopic history, Positive whiff test (i.e., the amine odor produced by mixing 10% potassium hydroxide solution with vaginal discharge sample), Metronidazole (Flagyl), 500 mg orally twice daily for seven days, Tinidazole (Tindamax), 2 g orally once daily for two days, Metronidazole, 500 mg orally twice daily for seven days, Routine treatment of sex partners is not recommended, Topical azole therapy applied intravaginally for seven days, Routine treatment of sex partners is not recommended unless the partner is symptomatic, Metronidazole, 2 g orally, single or divided dose on the same day, Metronidazole, 2 g orally, single dose in any stage of pregnancy, Differentiate persistent or recurrent infection from reinfection, Concurrent treatment of sex partners is recommended, Clotrimazole 1% cream, 5 g intravaginally daily for seven to 14 days, Clotrimazole 2% cream, 5 g intravaginally daily for three days, Miconazole 2% cream, 5 g intravaginally daily for seven days, Miconazole 4% cream, 5 g intravaginally daily for three days, Miconazole 100-mg vaginal suppository, one suppository daily for seven days, Miconazole 200-mg vaginal suppository, one suppository daily for three days, Miconazole 1,200-mg vaginal suppository, one suppository for one day, Tioconazole 6.5% ointment, 5 g intravaginally in a single application, Butoconazole 2% cream (Gynazole-1, single-dose bioadhesive product), 5 g intravaginally in a single application, Terconazole 0.4% cream, 5 g intravaginally daily for seven days, Terconazole 0.8% cream, 5 g intravaginally daily for three days, Terconazole 80-mg vaginal suppository, one suppository daily for three days. But sometimes brown discharge can be a sign of an illness or infection that requires medical attention. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. Brown Discharge After Period Causes, and When to See a Doctor - Healthline FLAGYL ER- metronidazole tablet, film coated, extended release. Women should be advised to return for treatment if symptoms recur. Find out how mixing this medication with alcohol can lead to serious side, Some pain, cramping, and discomfort during menstrual periods is normal. Another possibility of such discharge is the concomitant use of Metronidazole with birth control pills. Noninfectious causes, including atrophic, irritant, allergic, and inflammatory vaginitis, are less common and account for 5% to 10% of vaginitis cases.